Frequently Asked Questions About Comfort Eze™
- Is Comfort Eze a proton pump inhibitor and how does it affect the production of gastrin?
- How does Comfort Eze work in the stomach to provide relief and what are the mechanisms of reaction?
- Is Comfort Eze safer than other materials that contain proton pump inhibitors which have been reported to increase gastrin and possible risks to cancer?
- How much more effective is Comfort Eze and why?
- How stable is Comfort Eze after formulating into a tablet?
- What other benefits does Comfort Eze provide?
- What are some activities that cause high body acidity?
- What is neutralization?
- What is a buffer?
- What are the effects of acid-neutralizing compositions to foods?
- What is known of the constituents of Comfort Eze?
- Is Comfort Eze effective in many different foods and beverages?
- Can Comfort Eze be a supplement or an alternative source for calcium, magnesium and potassium?
- What is the effect of the magnesium hydroxide in Comfort Eze?
- What are the effects of food grade gum acacia?
- What is the effect of the acid neutralizing composition of Comfort Eze?
- Is the composition of Comfort Eze generally regarded as safe (GRAS)?
- What is meant by “safe and effective amount”?
- What is an “Alkaline body”?
- What are some acid and alkaline foods?
- How can Comfort Eze aid in adjusting the pH of the "body fluids" into an acceptable range, between 7.0 and 7.5, which will then influence the blood to maintain its optimal 7.35 pH level?
- What are the GRAS citations for each of the constituents of Comfort Eze?
- Why can’t I just blend up powders and make my own Comfort Eze formula?
- What is pKa?
Q: Is Comfort Eze a proton pump inhibitor and how does it affect the production of gastrin?
A: Comfort Eze is not a proton pump inhibitor, it does not influence the (hormonal control) gastrin production.
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Q: How does Comfort Eze work in the stomach to provide relief and what are the mechanisms of reaction?
A: Comfort Eze influences the gastrointestinal (GI) smooth muscle, mucosa and blood vessels by buffering acidic secretions that irritate the GI tract. Comfort Eze contains H+ (positive hydrogen) ions in combination with calcium, magnesium and potassium. This combination allows the calcium, magnesium and potassium to be more effective in neutralizing acid that causes irritation, restores oxygen to the blood and soothes irritated tissues.
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Q: Is Comfort Eze safer than other materials that contain proton pump inhibitors which have been reported to increase gastrin and possible risks to cancer?
A: We cannot provide any data on proton pump inhibitors and their links to cancer. There is data available that refers to endocrine secretions, specifically gastrin, that suggests there is increased gastrin production influenced by proton pumps. Comfort Eze is a safe, extremely fast acting and effective supplement that does not increase gastrin production.
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Q: How much more effective is Comfort Eze and why?
A: Our testing shows that Comfort Eze is faster acting in buffering hydrochloric acid from time zero to one minute after consumption.
Click on image to view a larger graph.
Comfort Eze is more effective because it has a stronger pKa (strength of the base) to initiate the buffering effect on the H+ ions allowing the buffering to react more quickly and over a longer time period.
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Q: How stable is Comfort Eze after formulating into a tablet?
A: Comfort Eze is very stable, up to five years, as long as moisture is avoided. All of the ingredients will activate with water or acids. All of the formulas are directly compressible and will function well with the normal excepients used in tableting.
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Q: What other benefits does Comfort Eze provide?
A: There is a great deal of emerging science on the alkaline condition of the body and possible benefits to overall health. Comfort Eze may help to promote a more alkaline system.
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Q: What are some activities that cause high body acidity?
A: The pH of the body is influenced by metabolic sub-products and our diet. Thus, pH is directly affected by the various categories of food that we eat and the internal mechanisms involved in their processing. Some foods that are acidic in their composition can become alkaline following metabolization, e.g. lemons. We are becoming more consciously aware of the impact that various food groups and our eating habits have on the internal environment of the body.
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Q: What is neutralization?
A: Neutralization does not necessarily mean attaining neutral pH (i.e., pH 7), rather, neutralization refers to the equivalence point for a particular acid-base reaction and will depend upon the respective strengths of the particular acid and base, their relative concentrations, and the buffering properties of the solution containing the acid and base.
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Q: What is a buffer?
A: A buffer is a solution containing salts of weak base that is capable of neutralizing both acids and bases and acts to maintain the pH of a solution. In other words, a buffered solution contains both a weak acid (e.g., acetic acid) and its conjugate weak base (e.g., sodium acetate) and its pH changes only slightly upon the addition of acid or base. The weak acid acts as a buffer when base is added to the solution, and the weak base acts as a buffer when acid is added to the solution.
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Q: What are the effects of acid-neutralizing compositions to foods?
A: The addition of an acid-neutralizing composition to an acidic food or beverage results in the neutralization of acids, thereby reducing the acidity of the food or beverage. At the same time, the food or beverage becomes buffered, that is, the pH of the food or beverage may be maintained, within limits, upon the addition of more acid.
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Q: What is known of the constituents of Comfort Eze?
A: The alkaline substances of Comfort Eze include alkaline earth metal carbonates, alkali and alkaline earth metal hydroxides. More specifically, alkaline earth metal carbonates include calcium and magnesium carbonates and dicalcium phosphate, and alkali and alkaline earth metal hydroxides include potassium and magnesium hydroxides. Alkaline substances having long-lasting antacid activity include alkali and alkaline earth metal carbonates. For example, the pharmaceutical use of calcium carbonate as an effective stomach antacid is well known. The rapid antacid effect of stronger alkaline substances such as alkali and alkaline earth metal hydroxides is also known. Commonly used alkali and alkaline earth metal hydroxides include lithium, sodium, potassium, calcium, and magnesium hydroxides.
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Q: Is Comfort Eze effective in many different foods and beverages?
A: The acid-neutralizing composition of Comfort Eze includes a combination of alkaline substances having both rapid and long-lasting antacid activity. As such, the composition of Comfort Eze is particularly well suited for reducing the acidity of caffeinated beverages such as coffee and tea or the acidity of orange or tomato juice. The rapid-acting alkaline substances (e.g., potassium hydroxide and magnesium hydroxide) of the composition effectively reduce the acidity of these beverages, while the long-lasting alkaline substances (e.g., calcium carbonate) counteract and neutralize acidic gastric secretions stimulated by the ingestion of caffeine. The alkaline substances noted in these formulas are the active ingredients primarily responsible for reducing the acidity of acidic foods and beverages. In addition to their antacid activity, the alkaline substances provide additional effects beneficial to health and nutrition.
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Q: Can Comfort Eze be a supplement or an alternative source for calcium, magnesium and potassium?
A: Yes, as reported that diets with higher levels of magnesium and potassium have less calcium loss from bones. Comfort Eze is another source for calcium, magnesium and potassium.
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Q: What is the effect of the magnesium hydroxide in Comfort Eze?
A: Magnesium hydroxide present in the composition has the effect of counteracting the constipative effect that often accompanies the ingestion of calcium carbonate. Furthermore, from a dietary standpoint, the alkaline substances also provide calcium, potassium, and magnesium, minerals for which the Food and Drug Administration has proposed minimum daily requirements. Magnesium hydroxide supplements the neutralizing effect of the potassium hydroxide, and is the second most active neutralizer. Calcium carbonate acts as a weak neutralizer, but also serves as a diluent to provide a convenient application quantity of the composition, and as a calcium source. The combination of these ingredients of the composition provides a highly effective acid neutralizer.
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Q: What are the effects of food grade gum acacia?
A: The acid-neutralizing composition of Comfort Eze includes gum acacia in an amount up to about 3% by weight of the total composition. The gum acacia is useful in the composition for neutralizing tannic acid, an acid present in the fruit of many plants, and one of the acids present in many foods and beverages.
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Q: What is the effect of the acid neutralizing composition of Comfort Eze?
A: The acid-neutralizing composition includes alkaline substances (i.e., calcium carbonate, magnesium carbonate, magnesium hydroxide, potassium hydroxide, dicalcium phosphate and gum acacia) that are active in reducing the acidity of an acidic food or beverage. All of these ingredients are generally regarded as safe (GRAS) for use by the Food and Drug Administration.
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Q: Is the composition of Comfort Eze generally regarded as safe (GRAS)?
A: Used in the amounts indicated, all of the ingredients of the antacid compositions of this invention are considered by the FDA to be generally regarded as safe (GRAS). For example, the standard manufacturing practice limit for potassium hydroxide is 1200 mg/serving. The composition of Comfort Eze, used as directed, the amount of potassium hydroxide administered is significantly less than the upper limits noted above.
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Q: What is meant by “safe and effective amount”?
A: The term "safe and effective amount" refers to a quantity of this supplement composition sufficient to provide the desired effect without undue adverse side effects such as toxicity, irritation, or allergic response. The specific safe and effective amount will vary with such factors as the specific condition that is being treated, the severity of the condition, the duration of the treatment, the physical condition of the subject, the nature of any concurrent therapy, and the specific formulation and optional components utilized. However, a human patient in need of such treatment will typically receive from about 200 mg to about 2000 mg of the composition daily.
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Q: What is an “Alkaline body”?
A: The scale that is used for measuring the pH, or the hydrogen ion concentration, is from 0 to 14, with 7.0 being the neutral point. Thus, an “Alkaline Body” pH means that the pH of the blood is above 7 with the ideal pH being 7.35. Outside of this range the body activity is no longer optimal and the metabolism is out of balance.
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Q: What are some acid and alkaline foods?
A: Acidic Foods … such as fast foods, coffee, tea, tomato and citrus products, meats, grains, greens, most fruits, refined salt, sugar, condiments (pickles, ketchup, etc.), soda pop etc., have a pH ranging from 2.8 to 5.5 which is highly acidic.
Alkaline Foods … almonds, all melons, unpasteurized honey, bee pollen, maple syrup, figs, dates, natural yogurt, cheese and dairy products, root vegetables, apricots, avocados, coconut, grapes, molasses, raisins and lemon.
An important fact to keep in mind is that the acid forming foods are important foods. They provide very important vitamins, minerals, proteins, fats and fiber. A diet is not complete without them. However, if these acid forming foods compose more than 20% of the diet, (for most Americans they compose over 90% of the diet) then as we age, and the body becomes less efficient, the cells of the body become more and more acidic. Though there are systems in place that maintain the delicate pH balance in the blood stream, at the cellular level a person can become more and more acidic. Many people who have serious illnesses have low pH values. Therefore, it is believed that the body pH is an important concept to understand.
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Q: How can Comfort Eze aid in adjusting the pH of the "body fluids" into an acceptable range, between 7.0 and 7.5, which will then influence the blood to maintain its optimal 7.35 pH level?
A: One of the key factors is the water that we drink. Water accounts for up to 75% of the body and thus the fluid intake greatly impacts the pH of the body. Unfortunately, a lot of the water that is being consumed is acidic - including distilled water, reverse osmosis, and deionized water - and have had minerals or buffers removed. Alkaline water is not readily or easily available in most communities. Supplementing Comfort Eze will aid in influencing the body fluids toward a more alkaline level.
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Q: What are the GRAS citations for each of the constituents of Comfort Eze?
A: All ingredients are designated as GRAS, as defined by the U.S. Food & Drug Administration, and contains a uniform mixture of the following items sourced from U.S. food grade or pharmaceutical grade ingredients: calcium carbonate, 21 CFR 184.1191; magnesium hydroxide, 21 CFR 184.1428; potassium hydroxide, 21 CFR 184.1631; dicalcium phosphate 21 CFR 182.1217 and gum acacia 21 CFR 184.1330.
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Q: Why can’t I just blend up powders and make my own Comfort Eze formula?
A: The formula and process are patented and protected under U.S. Patent laws. Any infringement on this patent is considered a violation of U.S. Patent laws. In order to achieve each of the performance parameters presented, the unique processing equipment utilized by SFS is needed to obtain a homogeneous mixture and even distribution of the Comfort Eze formula.
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Q: What is pKa?
A: Acids and bases can be classified as proton donors and proton acceptors, respectively. This means that the conjugate base of a given acid will carry a net charge that is more negative than the corresponding acid. In biologically relevant compounds, various weak acids and bases are encountered, e.g. the acidic and basic amino acids, nucleotides, phospholipids etc.
Weak acids and bases in solution do not fully dissociate and therefore there is equilibrium between the acid and its conjugate base. This equilibrium can be calculated and is termed the equilibrium constant = Ka. This is also sometimes referred to as the dissociation constant as it pertains to the dissociation of protons from acids and bases.
| pOH = -log[OH-] |
the negative log of the hydroxide ion molarity |
| pKw = -log Kw |
the negative log of the water ion product , Kw |
| pKa = -log Ka |
the negative log of the acid dissociation constant, Ka |
| pKb = -log Kb |
the negative log of the base dissociation constant, Kb |
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Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.
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